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Featuring DEP ES Neo, the latest generation of Dermoelectroporation® technology, this needle-free, AI-powered hair growth treatment enhances the delivery of spider silk protein and a seven-growth-factor complex into the scalp for hair loss treatment.
Category | Hair booster treatment (in-clinic, needle-free) |
Technology | DEP ES Neo – Dermoelectroporation®, AI-monitored |
Active complex | Spider silk protein + seven-growth-factor complex |
Works well with | Standalone, or alongside a microneedling programme |
Session length | 60 or 90 minutes |
Price | Trial available at $48 |
DEP Silk Hair Booster Treatment is TrichoLab’s needle-free scalp treatment that delivers spider silk protein and a seven-growth-factor complex through DEP ES Neo, the newest generation of Dermoelectroporation technology on the market.
It’s built to relieve hair loss, calm an irritated or dry scalp, strengthen the scalp barrier, and support fuller-looking hair root volume, in a single 60- or 90-minute session.
DEP Silk Hair Booster Treatment is Singapore’s first hair booster treatment built for the scalp. It is effective as a standalone treatment, and an excellent addition to our existing microneedling treatment for clients who want to accelerate results.
Instead of leaving actives to absorb passively through the scalp’s surface, DEP Es Neo Technology opens the scalp’s own water-based channels and carry the complex toward the follicle with AI-monitored electrical pulses.
Greater introduction rate
DEP ES Neo drives active ingredients into the scalp up to 17x faster than topical application left to absorb on its own.
Improved absorption
DEP ES Neo boosts absorption of ionic and larger-molecule actives by up to 80% versus topical-only application.
Molecular weight ceiling
DEP can carry molecules beyond 800 kDalton through the scalp's channels — well past what standard iontophoresis can move.
Needles, pain, or downtime
There is no pH disruption, electrolysis effect on the serum and recovery time.
The “Neo” in DEP ES Neo represents AI Sense software, which continuously reads the scalp’s impedance and automatically adjusts pulse parameters throughout the treatment.
A real-time Delivery Display also lets our hair specialists see exactly when active ingredients are being absorbed, and alerts them when they are not, helping ensure every treatment is delivered with highest accuracy.
Older DEP and iontophoresis systems still used by most scalp clinics in Singapore operate on fixed settings, relying on the therapist to judge whether the treatment is being delivered effectively.
DEP ES Neo | Older DEP/iontophoresis |
AI-monitored electrical pulses open water-based channels | Fixed-setting electrical delivery, manually tuned |
Spider silk protein is a biofermented protein engineered to recreate the molecular structure of natural spider silk, one of the strongest and most elastic fibres in nature, without involving any actual spiders.
Grown through an advanced biofermentation process rather than harvested, it is naturally rich in amino acids that support a healthier scalp environment, including glycine, alanine, serine and proline.
Glycine
Supports collagen synthesis in the skin barrier and scalp environment.
Alanine
Helps regulate moisture at the epidermal level.
Serine & proline
Supports keratin production, the structural protein hair itself is made of.
Spider silk protein’s porous molecular architecture also functions as a natural scaffold, providing a supportive framework for cells to attach to and proliferate. This unique structure makes it an ideal delivery partner for the seven-growth-factor complex in TrichoLab’s DEP Silk Hair Booster Treatment, helping to improve its distribution and interaction within the scalp.
The seven-growth-factor complex used in TrichoLab’s DEP Silk Hair Booster Treatment is a proprietary blend of seven growth factors formulated to support the natural hair growth cycle.
They help encourage healthy follicle activity, promote keratin production, support nutrient delivery to the hair follicle, and maintain the environment needed for healthier hair growth.
To improve delivery, the growth factors are encapsulated in liposomes –tiny microscopic carriers that can pass through both the water– and oil-based layers of the scalp. This helps protect the active ingredients and allows them to reach the hair follicles more effectively.
Growth Factor | Supports |
IGF | Hair follicle growth and activity |
KGF (FGF-7) | Keratin production and hair shaft formation |
VEGF | Blood vessel formation and nutrient delivery to follicles |
FGF-α / FGF-β | Cell renewal and follicle metabolism |
TGF-β | Tissue remodelling and the follicle’s growth-cycle signalling. |
SCF | Hair follicle stem cell support |
DEP Silk Hair Booster Treatment and microneedling are two complementary hair restoration treatments with distinct mechanisms of action.
While each is effective as a standalone treatment, combining them allows you to target hair loss in more holistic ways – microneedling to activate the scalp’s natural regenerative response, DEP to enhance the delivery of growth-promoting ingredients deep into the scalp.
DEP Silk Hair Booster Treatment | Signature Medical Microneedling Hair Growth Treatment | |
How it works | AI-monitored electrical pulses open the scalp’s water-based channels to carry actives deep, needle-free | Fine needles create controlled micro-injury to trigger the scalp’s own repair and growth response |
What it delivers | Spider silk protein + seven-growth-factor complex | Whatever serum is paired with it, plus the mechanical stimulation itself |
Downtime | None | Minimal, may show light redness |
DEP Silk Hair Booster Treatment is available from an introductory trial price of $48. Every session includes a comprehensive scalp analysis before and after treatment, so you can monitor changes in your scalp health and hair growth throughout your treatment journey.
DEP Silk Hair Booster Treatment is a needle-free scalp treatment that delivers spider silk protein and a seven-growth-factor complex through DEP ES Neo, the latest Dermoelectroporation® technology. It relieves shedding, calms scalp dryness and itchiness, and strengthens the scalp barrier. This treatment can be done on its own, or alongside a microneedling programme.
No. DEP Silk works as a standalone hair booster treatment. If you’re already on a microneedling programme, adding DEP Silk is a great way to compound results, but it isn’t a requirement to get started.
DEP Silk uses AI-monitored electrical pulses to carry a spider silk and growth factor complex through the scalp’s own channels, needle-free. Microneedling uses fine needles to create controlled micro-injury that triggers the scalp’s repair response. Both can be booked on their own, and many clients pair the two for a faster combined result.
DEP ES Neo is the latest generation of the technology, with AI Sense software that reads the scalp’s impedance and adjusts pulse settings automatically, plus a real-time delivery display so the therapist can see absorption happening rather than relying on a fixed-setting device.
DEP Silk Hair Booster Treatment is a needle-free, non-invasive treatment with no downtime. Most clients feel a light tingling sensation at most; there is no burning or pH disruption. You can return to normal activities immediately.
Inside this serum, exclusive to TrichoLab, is a biofermented spider silk protein and a proprietary seven-growth-factor complex (FGF-α, FGF-β, VEGF, TGF-β, IGF, KGF and SCF), formulated in liposome form for delivery through both the water- and oil-based layers of the scalp.
DEP Silk Hair Booster Treatment is available exclusively at TrichoLab from $298. We offer a full trial session from $48.
Clients running DEP Silk Hair Booster Treatment as a standalone typically book every few weeks as part of ongoing scalp maintenance. Those pairing it with microneedling usually slot it into the weeks between microneedling appointments, so there’s continuous momentum across the programme.
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